13(18)-Oleanen-3-one | CAS 20248-08-2

δ-Amyrone(13(18)-Oleanen-3-one), a specific inhibitor of cyclooxygenase-2, possesses anti-inflammatory effects, which may be relevant to the regulation of COX-2; it exerts its protective effect on experimental gastric ulcer by inhibiting NF-κB signaling pathways, which subsequently reduces overproduction of the inducible enzymes iNOS and suppresses the release of the inflammatory factors TNF-α, IL-6 and NO. δ-Amyrone has protective activity on LPS-induced endotoxic shock, which is attributed to reducing NO production and mediating the pro-inflammatory cytokines, inhibited NF-κB expression.

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Product Name	13(18)-Oleanen-3-one
CAS No.:	20248-08-2
Catalog No.:	CFN98023
Molecular Formula:	C₃₀H₄₈O
Molecular Weight:	424.7 g/mol
Purity:	>=98%
Type of Compound:	Triterpenoids
Physical Desc.:	Cryst.
Source:	The herbs of Euphorbia supina
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
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