17alpha-Estradiol

Structure

Summary

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Description

17Alpha-estradiol is a potent estrogen and carcinogen during development. 17Alpha-estradiol has neuroprotective activity, it is effective in lowering cerebral amyloid-beta levels in AbetaPPSWE transgenic mice, it may help to develop safe and effective therapeutics to treat Alzheimer disease. 17Alpha-estradiol induces aromatase activity in isolated human hair follicles, it may be used for topical treatment of androgenetic alopecia (AGA) in women. 17Alpha-estradiol also arrests cell cycle progression at G2/M and induces apoptotic cell death in human acute leukemia Jurkat T cells.

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Storage

Recommended storage conditions and precautions regarding proper product handling are contained in the product Certificate of Analysis (COA). Here are general storage guidelines for compounds:

Powder: -20°C 3 years and 4°C 2 years
In solvent: -80°C 6 months and -20°C 1 month

If the solution is stored at -20°C for more than one month, it should be re-examined to ensure its efficacy. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their COAs.

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After receiving

The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Product Name	17alpha-Estradiol
CAS No.:	57-91-0
Catalog No.:	CFN96786
Molecular Formula:	C₁₈H₂₄O₂
Molecular Weight:	272.38 g/mol
Purity:	>=98%
Type of Compound:	Steroids
Physical Desc.:	Powder
Source:	The seed oil of Punica granatum L.
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
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