7,8-Dihydroxyflavone
7,8-Dihydroxyflavone(7,8-DHF) shows vasorelaxing , antihypertensive, anti-inflammatory and anti-oxidant properties, it can be used as a potent facultative ingredient in health-beneficial agents to prevent or treat the skin aging or inflammatory skin disorders. 7,8-DHF has anti-obesity activity, it improves mitochondrial respiration in STs from obese women, it is beneficial for both depression and anxiety-like behaviors, and may exert fast-onset antidepressant effects. 7,8-DHF exhibits anti-melanogenic activity through inhibition of tyrosinase activity in α-MSH-stimulating condition, it also shows anticancer activity in melanoma cells via downregulation of α-MSH/cAMP/MITF pathway. 7,8-DHF ameliorates motor deficits via suppressing α-synuclein expression and oxidative stress in the MPTP-induced mouse model of Parkinson's disease.
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Recommended storage conditions and precautions regarding proper product handling are contained in the product Certificate of Analysis (COA). Here are general storage guidelines for compounds:
Powder: -20°C 3 years and 4°C 2 years
In solvent: -80°C 6 months and -20°C 1 month
If the solution is stored at -20°C for more than one month, it should be re-examined to ensure its efficacy. Avoid repeated freeze and thaw cycles.
Storage conditions for some special products should refer to their COAs.
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The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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