Amphotericin B | CAS 1397-89-3

Amphotericin B is an antifungal agent. Amphotericin B can regulate inflammatory cytokines in host cells and regulate inflammatory responses in HGEC, it inhibits the A. actinomycetemcomitans-induced phosphorylation of ERK and p38 MAP kinase. Amphotericin B inhibits the A. actinomycetemcomitans-induced production of prostaglandin E2, the inhibition of the PKA signaling pathway can aid in reducing the degree of nephrotoxicity caused by Amphotericin B. Treatment with amphotericin B, particularly in combination with MCSF, increased the number of oligodendrocyte precursor cells and promoted remyelination within lesions.

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Recommended storage conditions and precautions regarding proper product handling are contained in the product Certificate of Analysis (COA). Here are general storage guidelines for compounds:

Powder: -20°C 3 years and 4°C 2 years
In solvent: -80°C 6 months and -20°C 1 month

If the solution is stored at -20°C for more than one month, it should be re-examined to ensure its efficacy. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their COAs.

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Product Name	Amphotericin B
CAS No.:	1397-89-3
Catalog No.:	CFN90422
Molecular Formula:	C₄₇H₇₃NO₁₇
Molecular Weight:	924.07 g/mol
Purity:	>=98%
Type of Compound:	Miscellaneous
Physical Desc.:	Powder
Source:	From Streptomyces nodosus
Solvent:	DMSO, Pyridine, Methanol, Ethanol, etc.
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