Cryptotanshinone | CAS 35825-57-1

Cryptotanshinone is a potent STAT3 inhibitor with IC50 of 4.6 μM, and inhibits STAT3 Tyr705 phosphorylation in DU145 prostate cancer cells. It is also an AR inhibitor to suppress androgen/AR-mediated cell growth and PSA expression by blocking AR dimerization and the AR-coregulator complex formation. Cryptotanshinone has anti-atherosclerosis, neuroprotective, anti-cancer,and anti-neointimal formation activities. Cryptotanshinone reverses DEX-induced androgen excess and ovarian IR in mice through activation of insulin signaling and the regulation of glucose transporters and hormone-synthesizing enzymes, it has an inhibitory effect on MMP-9 production and migration of human aortic smooth muscle cells treated with TNF-alpha in a dose-dependent manner.

Inquire / Order: manager@chemfaces.com
Technical Inquiries: service@chemfaces.com
Tel: +86-27-84237783
Fax: +86-27-84254680

Address:
1 Building, No. 176, CheCheng West Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC

Recommended storage conditions and precautions regarding proper product handling are contained in the product Certificate of Analysis (COA). Here are general storage guidelines for compounds:

Powder: -20°C 3 years and 4°C 2 years
In solvent: -80°C 6 months and -20°C 1 month

If the solution is stored at -20°C for more than one month, it should be re-examined to ensure its efficacy. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their COAs.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Product Name	Cryptotanshinone
CAS No.:	35825-57-1
Catalog No.:	CFN98478
Molecular Formula:	C₁₉H₂₀O₃
Molecular Weight:	296.4 g/mol
Purity:	>=98%
Type of Compound:	Diterpenoids
Physical Desc.:	Red powder
Source:	The roots of Salvia miltiorrhiza Bge.
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Price:	$30/20mg

Name:	*
E-mail:	*
Expected:	I would like to request a price quotation for Cryptotanshinone. Do you have a bulk discount? I want to order the Cryptotanshinone, Would you please let me know a distributor in local. I would like to purchase of Cryptotanshinone, Is it purchasable? if possible, Could you give me more information for price, amount, and delivery time.
Message:	*
CheckCode:
	* Welcome to our website. If you have any questions, please send a message to us. We'll do our best to get back to you within 24 hours.