Cycloastragenol | CAS 84605-18-5

Cycloastragenol has been shown to extend T cell proliferation by increasing telomarase activity showing that it may also help delay the onset of cellular aging; it is an extraordinary wound healing agent; it inhibits the apoptosis of PC12 induced by 6-OHDA, may be as potential neuroprotective agents in the treatment of Parkinson's disease. Cycloastragenol and astragaloside IV can suppress ROS-associated ER stress and then inhibit TXNIP/NLRP3 inflammasome activation with regulation of AMPK activity, and thereby ameliorate endothelial dysfunction by inhibiting inflammation and reducing cell apoptosis. Cycloastragenol and astragaloside IV have been shown to improve the proliferative response of CD8+ T lymphocytes from HIV-infected patients by upregulating telomerase activity, they also may exert their cellular effects through the activation of the Src/MEK/ERK pathway.

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Recommended storage conditions and precautions regarding proper product handling are contained in the product Certificate of Analysis (COA). Here are general storage guidelines for compounds:

Powder: -20°C 3 years and 4°C 2 years
In solvent: -80°C 6 months and -20°C 1 month

If the solution is stored at -20°C for more than one month, it should be re-examined to ensure its efficacy. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their COAs.

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The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Product Name	Cycloastragenol
CAS No.:	84605-18-5
Catalog No.:	CFN99538
Molecular Formula:	C₃₀H₅₀O₅
Molecular Weight:	490.71 g/mol
Purity:	>=98%
Type of Compound:	Triterpenoids
Physical Desc.:	Powder
Source:	The roots of Astragalus membranaceus (Fisch.) Bunge
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Price:	$30/20mg

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