Cyclovirobuxine | CAS 860-79-7

Cyclovirobuxine D(CVB-D) has vasorelaxant effect, it has been widely used for treatment of cardiac insufficiency and arrhythmias in China, the antiarrhythmic and proarrhythmic potential of this drug might be concerned with prolongation of action potential duration and QT interval. CVB-D can induce autophagy in the MCF-7 human breast cancer cell line by attenuating the phosphorylation of Akt and mTOR , CVB-D-induced autophagy and decrease in cell viability could be blocked by 3-methyladenine, a well-established autophagy inhibitor.

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Recommended storage conditions and precautions regarding proper product handling are contained in the product Certificate of Analysis (COA). Here are general storage guidelines for compounds:

Powder: -20°C 3 years and 4°C 2 years
In solvent: -80°C 6 months and -20°C 1 month

If the solution is stored at -20°C for more than one month, it should be re-examined to ensure its efficacy. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their COAs.

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The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Product Name	Cyclovirobuxine
CAS No.:	860-79-7
Catalog No.:	CFN99176
Molecular Formula:	C₂₆H₄₆N₂O
Molecular Weight:	402.66 g/mol
Purity:	>=98%
Type of Compound:	Alkaloids
Physical Desc.:	White cryst.
Source:	The barks of Buxus sinica var. parvifolia M. Cheng.
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Price:	$30/20mg

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