Fucosterol
Fucosterol possesses anti-oxidant, hepatoprotective, cytotoxic, antihistaminic, anticholinergic and antiviral activities. Fucosterol exhibits anti-inflammatory activity which might attribute to inhibition of NO and ROS generation and suppression of the NF-κB pathway. Fucosterol also has anti-diabetic activity in vivo, it exhibits an inhibition of sorbitol accumulations in the lenses and causes an inhibition of blood glucose level and glycogen degradation. Fucosterol is a dual-LXR agonist that regulates the expression of key genes in cholesterol homeostasis in multiple cell lines without inducing hepatic triglyceride accumulation; it could as an anti-obesity agent, it can inhibit expression of PPARγ and C/EBPα, resulting in a decrease of lipid accumulation in 3T3-L1 pre-adipocytes.
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Recommended storage conditions and precautions regarding proper product handling are contained in the product Certificate of Analysis (COA). Here are general storage guidelines for compounds:
Powder: -20°C 3 years and 4°C 2 years
In solvent: -80°C 6 months and -20°C 1 month
If the solution is stored at -20°C for more than one month, it should be re-examined to ensure its efficacy. Avoid repeated freeze and thaw cycles.
Storage conditions for some special products should refer to their COAs.
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The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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