Galgravin

Galgravin
Product Name Galgravin
CAS No.: 528-63-2
Catalog No.: CFN93059
Molecular Formula: C22H28O5
Molecular Weight: 372.46 g/mol
Purity: >=98%
Type of Compound: Lignans
Physical Desc.: Powder
Source: The flowers of Magnolia biondii
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
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Galgravin has anti-inflammatory, and neuroprotective effects, it can promote neuronal survival and neurite outgrowth, protect hippocampal neurons against amyloid beta peptide (Abeta25-35)-induced cytotoxicity, and protect against neuronal death from 1-methyl-4-phenylpyridinium ion (MPP+)-induced toxicity in cultured rat hippocampal neurons. Galgravin has cytotoxic activity against human leukemia (HL-60) tumor cells with the IC50 value of 16.5 ± 0.8 ug/mL. Galgravin also can inhibit bone resorption and may offer a novel compounds for the development of drugs to treat bone-destructive diseases such as osteoporosis.
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Recommended storage conditions and precautions regarding proper product handling are contained in the product Certificate of Analysis (COA). Here are general storage guidelines for compounds:

Powder: -20°C 3 years and 4°C 2 years
In solvent: -80°C 6 months and -20°C 1 month

If the solution is stored at -20°C for more than one month, it should be re-examined to ensure its efficacy. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their COAs.

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The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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