Gigantol | CAS 67884-30-4

Gigantol is a novel inhibitor of the Wnt/β-catenin pathway, it inhibits Wnt/β-catenin signaling through downregulation of phosphorylated LRP6 and cytosolic β-catenin in breast cancer cells, it induces growth inhibition and apoptosis of HepG2 cells via the PI3K/Akt/NF-κB signaling pathway. Gigantol may be developed as a promising neuroprotective agent for successful MSC transplantation in ischemic diseases, it shows protective effect against hydrogen peroxide-induced apoptosis in rat bone marrow mesenchymal stem cells through the PI3K/Akt pathway. Gigantol inhibits aldose reductase gene to exert its anti-cataract activity. Gigantol also shows α-glucosidase inhibitory activity.

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Recommended storage conditions and precautions regarding proper product handling are contained in the product Certificate of Analysis (COA). Here are general storage guidelines for compounds:

Powder: -20°C 3 years and 4°C 2 years
In solvent: -80°C 6 months and -20°C 1 month

If the solution is stored at -20°C for more than one month, it should be re-examined to ensure its efficacy. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their COAs.

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The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Product Name	Gigantol
CAS No.:	67884-30-4
Catalog No.:	CFN93035
Molecular Formula:	C₁₆H₁₈O₄
Molecular Weight:	274.31 g/mol
Purity:	>=98%
Type of Compound:	Phenols
Physical Desc.:	Oil
Source:	The herbs of Dendrobium chrysotoxum
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Price:	$218/10mg

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