Glibenclamide

Glibenclamide
Product Name Glibenclamide
CAS No.: 10238-21-8
Catalog No.: CFN80103
Molecular Formula: C23H28ClN3O5S
Molecular Weight: 494.00 g/mol
Purity: >=98%
Type of Compound: Alkaloids
Physical Desc.: Powder
Source:
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Price: $30/20mg
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Glibenclamide is a known blocker of vascular ATP-sensitive K+ channels (KATP), used in the treatment of type 2 diabetes.Glibenclamide increases the risk for hypoglycemia by increasing insulin secretion, it plays a paradoxical protective role to protect against severe hypoglycemia-induced fatal cardiac arrhythmias; it also reduces inflammation, vasogenic edema, and caspase-3 activation after subarachnoid hemorrhage.
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Recommended storage conditions and precautions regarding proper product handling are contained in the product Certificate of Analysis (COA). Here are general storage guidelines for compounds:

Powder: -20°C 3 years and 4°C 2 years
In solvent: -80°C 6 months and -20°C 1 month

If the solution is stored at -20°C for more than one month, it should be re-examined to ensure its efficacy. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their COAs.

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The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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