Harpagoside | CAS 19210-12-9

Harpagoside has anti-inflammatory effects, it blocks lipopolysaccharide (LPS)-induced bone loss in an inflammatory osteoporosis model, and it does not prevent ovariectomy-mediated bone erosion in a postmenopausal osteoporosis model, it may lead to a partial prevention of obesity-induced atherosclerosis by attenuating inflammatory responses. Harpagoside suppresses lipopolysaccharide-induced iNOS and COX-2 expression through inhibition of NF-κB activation. Harpagoside exerts neuroprotection effect and ameliorates learning and memory deficit appears to be associated, at least in part, with up-regulation of brain-derived neurotrophic factor (BDNF) content as well as activating its downstream signaling pathways, e.g., MAPK/PI3K pathways.

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Powder: -20°C 3 years and 4°C 2 years
In solvent: -80°C 6 months and -20°C 1 month

If the solution is stored at -20°C for more than one month, it should be re-examined to ensure its efficacy. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their COAs.

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Product Name	Harpagoside
CAS No.:	19210-12-9
Catalog No.:	CFN98147
Molecular Formula:	C₂₄H₃₀O₁₁
Molecular Weight:	494.49 g/mol
Purity:	>=98%
Type of Compound:	Iridoids
Physical Desc.:	White cryst.
Source:	The roots of Scrophularia ningpoensis Hemsl.
Solvent:	DMSO, Pyridine, Methanol, Ethanol, etc.
Price:	$70/20mg

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