Helenalin
Helenalin is a promising experimental cytotoxic agent that possibly points to new strategies to overcome apoptosis resistance attributable to overexpression of antiapoptotic Bcl-2 proteins. Helenalin is a new immunosuppressive compound suited for the treatment of deregulated and unwanted T cell-mediated immune responses. Helenalin has anti-inflammatory activity, it inhibits the transcription factor NF-kappaB by directly targeting p65. Helenalin has anti-trypanosomal activity against the African Trypanosoma brucei rhodesiense and American T. cruzi.; it reduces Staphylococcus aureus infection in vitro and in vivo.
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Recommended storage conditions and precautions regarding proper product handling are contained in the product Certificate of Analysis (COA). Here are general storage guidelines for compounds:
Powder: -20°C 3 years and 4°C 2 years
In solvent: -80°C 6 months and -20°C 1 month
If the solution is stored at -20°C for more than one month, it should be re-examined to ensure its efficacy. Avoid repeated freeze and thaw cycles.
Storage conditions for some special products should refer to their COAs.
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The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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