Isorhamnetin 3-glucuronide | CAS 36687-76-0

Isorhamnetin 3 -O -glucuronide exerts anti-inflammatory activity by increasing heme oxygenase-1 (HO-1) expression and by suppressing Jun N-terminal kinase (JNK) and p38 signaling pathways in LPS-challenged RAW264.7 macrophage cells. Isorhamnetin 3-glucuronide can inhibit vascular cell adhesion molecule-1 (VCAM-1) cell surface expression at 2 micromol/L, indicates that it can inhibit the expression of key molecules involved in monocyte recruitment during the early stages of atherosclerosis at physiological concentrations. It (1 mg/kg i.v.) can progressively reduce mean blood pressure (MBP), measured in conscious spontaneously hypertensive rats (SHR).

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In solvent: -80°C 6 months and -20°C 1 month

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Product Name	Isorhamnetin 3-glucuronide
CAS No.:	36687-76-0
Catalog No.:	CFN90568
Molecular Formula:	C₂₂H₂₀O₁₃
Molecular Weight:	492.39 g/mol
Purity:	>=98%
Type of Compound:	Flavonoids
Physical Desc.:	Powder
Source:	The herbs of Potentilla discolor Bge.
Solvent:	DMSO, Pyridine, Methanol, Ethanol, etc.
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