Morolic acid
Morolic acid and moronic acid have shown sustained antidiabetic and antihyperglycemic action possibly mediated by an insulin sensitization with consequent changes of glucose, cholesterol and triglycerides, in part mediated by inhibition of 11β-HSD 1. Morolic acid exhibits pronounced radical scavenging activity against the stable 2,2-diphenyl-1-picrylhydrazyl radical and is a potent inhibitor of neutrophil elastase and cyclooxygenase-1 and -2 in vitro.
Morolic acid has anti- inflammatory activity, it can inhibit leukotriene B4 production in rat polymorphonuclear leukocytes stimulated with calcium ionophore A 23187. Morolic acid exhibits promising anti-HIV activity, it also exhibits moderate inhibitory activity against glycogen phosphorylase.
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Recommended storage conditions and precautions regarding proper product handling are contained in the product Certificate of Analysis (COA). Here are general storage guidelines for compounds:
Powder: -20°C 3 years and 4°C 2 years
In solvent: -80°C 6 months and -20°C 1 month
If the solution is stored at -20°C for more than one month, it should be re-examined to ensure its efficacy. Avoid repeated freeze and thaw cycles.
Storage conditions for some special products should refer to their COAs.
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The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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