Tauroursodeoxycholic acid | CAS 14605-22-2

Tauroursodeoxycholic acid (TUDCA) may enhance the secretory capacity of cholestatic hepatocytes by stimulation of exocytosis and insertion of transport proteins into apical membranes via PKC-dependent mechanisms. TUDCA acts as a chemical chaperone to enhance protein folding and ameliorate ER stress, increases insulin sensitivity, it may be an effective pharmacological approach for treating insulin resistance. TUDCA has wide-range neuroprotective effects, it is a strong modulator of AbetaE22Q-triggered apoptosis, it may provide a potentially useful treatment in patients with hemorrhagic stroke and perhaps other acute brain injuries associated with cell death by apoptosis.

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Recommended storage conditions and precautions regarding proper product handling are contained in the product Certificate of Analysis (COA). Here are general storage guidelines for compounds:

Powder: -20°C 3 years and 4°C 2 years
In solvent: -80°C 6 months and -20°C 1 month

If the solution is stored at -20°C for more than one month, it should be re-examined to ensure its efficacy. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their COAs.

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Product Name	Tauroursodeoxycholic acid
CAS No.:	14605-22-2
Catalog No.:	CFN96645
Molecular Formula:	C₂₆H₄₅NO₆S
Molecular Weight:	499.70 g/mol
Purity:	>=98%
Type of Compound:	Steroids
Physical Desc.:	Powder
Source:	From bear biliary.
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
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