U0126-EtOH

U0126-EtOH
Product Name U0126-EtOH
CAS No.: 1173097-76-1
Catalog No.: CFN60004
Molecular Formula: C20H22N6OS2
Molecular Weight: 426.6 g/mol
Purity: >=98%
Type of Compound: Inhibitors
Physical Desc.: Powder
Source:
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
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U0126-EtOH is a highly selective inhibitor of MEK1/2 with IC50 of 0.07 μM/0.06 μM in cell-free assays, 100-fold higher affinity for ΔN3-S218E/S222D MEK than PD98059. U0126 inhibits autophagy and mitophagy with antiviral activity.
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Recommended storage conditions and precautions regarding proper product handling are contained in the product Certificate of Analysis (COA). Here are general storage guidelines for compounds:

Powder: -20°C 3 years and 4°C 2 years
In solvent: -80°C 6 months and -20°C 1 month

If the solution is stored at -20°C for more than one month, it should be re-examined to ensure its efficacy. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their COAs.

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The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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